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The clinical efficacy of the procedure has been difficult to prove. We evaluated the relationship of TMR to six preoperative and nine postoperative variables. The database from 100 consecutive patients who underwent TMR and CABG was reviewed. Patients were followed for at least 1 year postoperatively. Univariate analysis of preoperative and postoperative variables was performed by chi-square, Pearson's, Spearman's, or Kruskal-Wallis test. Multivariate analysis of preoperative and postoperative variables was performed by stepwise multiple logistic regression, and included all variables that were significant by univariate analysis. Mean age was 53.7 +/- 11.7 years, mean left ventricular ejection fraction was 47.8% +/- 16.3%, and mean number of diseased coronary vessels was 3.6 +/- 0.8. The percentage of males was significantly higher (86% vs. 52%; p = 0.0001). Revascularization was electively performed in 57 patients (57%) and emergently in 43 (43%). The mean follow-up was 14.9 +/- 8.2 months. There were 11 deaths in the follow-up period. The overall survival rate was 93% at 1 year and 86% at 2 years. The hospital mortality rate was 6%. Rehospitalization for coronary events occurred in seven patients. Multivariate analysis revealed only two variables were predictive of mortality and hospitalization: age, inversely related (p = 0.0002), and beta-blocker use, directly related (p = 0.0004). TMR was not found to be predictive of mortality and hospitalization. Although the number of diseased coronary vessels and left ventricular ejection fraction were related to mortality, age was the only independent predictor of mortality. 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